The Albegna Valley, located in the north-western territory of Vulci, has been identified as an important Etruscan agricultural district, specialised in Etruscan wine production. Surveys and excavations promoted in the areas facing Marsiliana d’Albegna and Doganella, highlighted important concentrations of transport amphorae and wasters, as well as structures for elaboration and storage of cultivated goods. These amphorae can be mainly divided between older types (A-ETR3A/B) and more recent ones (A-ETR3C). The present study focuses on the local transport amphorae, detecting the wine trade to the coasts of the Gulf of Lion, during the 6th century BC. An archaeometric investigation was carried out on 150 samples of amphorae coming from the two Etruscan centres, such as from other sites of the Albegna Valley, in order to compare them with Etruscan amphorae detected from the ports of Lattara and Emporion. The study was able to identify changes in amphorae production between the 6th and the first half of the 5th centuries BC, and to see how the production of wine from the Albegna area has been recorded in the ports of Celtic and Iberian coasts.